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Biomarker intelligence

Understand what your biology is telling you.

What common lab markers measure, why each one matters, and how markers connect across your biological systems. Educational information only. Pepvela does not diagnose, interpret individual results or replace a licensed clinician.

03System

Hormonal

Sex hormones, thyroid and stress signalling, and the proteins that carry them.

Cortisol

AM Serum Cortisol

A steroid hormone produced by the adrenal glands that follows a daily rhythm, commonly reviewed in adrenal-related and hormone-related lab panels. Educational context only.

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DHEA-S

Dehydroepiandrosterone Sulfate

Dehydroepiandrosterone sulfate, an adrenal androgen-related marker commonly reviewed alongside testosterone, SHBG, and other hormone markers. Educational context only.

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Estradiol

Estradiol (E2)

Estradiol (E2), a major form of estrogen present in all sexes, commonly reviewed alongside testosterone, SHBG, and other sex hormone markers. Educational context only.

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Free Testosterone

Free Testosterone (unbound fraction)

The unbound fraction of testosterone not attached to SHBG or albumin, commonly reviewed alongside total testosterone and SHBG. Method-dependent. Educational context only.

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LH & FSH

Luteinizing Hormone & Follicle Stimulating Hormone

Pituitary hormones that provide pituitary-gonadal signaling context, commonly reviewed alongside testosterone, SHBG, and free testosterone. Educational context only.

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SHBG

Sex Hormone Binding Globulin

Sex hormone-binding globulin, the hormone-binding protein made mainly by the liver that binds testosterone and estradiol and adds context alongside total and free testosterone. Educational context only.

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Testosterone

Testosterone Biomarkers (Overview)

Overview of the testosterone-related markers — total testosterone, free testosterone, SHBG, LH, FSH, and DHEA-S — and how they are reviewed together. Educational context only.

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Total Testosterone

Total Testosterone (bound + unbound)

A commonly measured hormone marker: the combined amount of testosterone circulating in the blood, reviewed alongside free testosterone and SHBG. Educational context only.

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TSH

Thyroid Stimulating Hormone

"The signal your brain sends to your thyroid, high TSH means the thyroid isn't responding enough, low TSH means it may be overactive."

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Reading biomarker information

Context matters more than any single number.

  • Reference ranges differ between laboratories, methods and populations. Your lab report states its own.
  • One result is a snapshot. Trends over time, and related markers, usually say more.
  • Interpretation belongs with a licensed clinician who knows your history. Pepvela provides education, not diagnosis.